Malignant melanoma is the most serious form of skin cancer arising from the pigment producing cells in the skin known as melanocytes. It is the most common cause of skin cancer death worldwide. Chances of curing melanoma are directly related to how deep it has grown in the skin when diagnosed. The earlier it is picked up, the higher the chance of cure. If left too late, melanoma has the ability to rapidly spread throughout the body. Melanoma most commonly arises from a new or changing mole on the skin, although it rarely can occur on the skid of the palms, the soles and even the nails.